Viral vectors for production of recombinant proteins in plants
نویسندگان
چکیده
منابع مشابه
Plant Viral Vectors as a Tool for Recombinant Vaccine Production
Over the last few years the development of plant viral vectors for protein expression has made rapid and impressive progress. Plant viruses are versatile vectors for production of proteins since they are easy to manipulate, quick to evaluate and offer the possibility of great production yields. They are particularly powerful expression systems for the production of recombinant proteins and pept...
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In recent years recombinant adeno-associated viral vectors (AAV) have become increasingly valuable for in vivo studies in animals, and are also currently being tested in human clinical trials. Wild-type AAV is a non-pathogenic member of the parvoviridae family and inherently replication-deficient. The broad transduction profile, low immune response as well as the strong and persistent transgene...
متن کاملPlants as factories for the Production of Pharmaceutical recombinant proteins
Nowadays, transgenic plants are used as an attractive alternative to produce recombinant pharmaceutical proteins. Recombinant proteins such as vaccines and antibodies can be produced in plants via two systemes: stable genetic transformation and transient expression. Stable transformation is included of integrating a gene into the plant nuclear or chloroplast genome. The transient expression can...
متن کاملSelecting appropriate hosts for recombinant proteins production: Review article
In recent years, the number of recombinant proteins used for therapeutic applications and industry has increased dramatically. Recombinant proteins are produced in many host organisms (microbial, insect, plant and mammalian cells). There are many factors to consider when choosing the optimal system for protein expression and purification including the mass, purity or solubility of the recombina...
متن کاملThe production of recombinant pharmaceutical proteins in plants.
Imagine a world in which any protein, either naturally occurring or designed by man, could be produced safely, inexpensively and in almost unlimited quantities using only simple nutrients, water and sunlight. This could one day become reality as we learn to harness the power of plants for the production of recombinant proteins on an agricultural scale. Molecular farming in plants has already pr...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2008
ISSN: 0021-9541,1097-4652
DOI: 10.1002/jcp.21423